After Anne Peled, M.D. was diagnosed with breast cancer at 37, she carefully weighed all of her options and opted for a lumpectomy rather than a mastectomy, in large part because of having to face the prospect of losing sensation if she opted for a mastectomy and implant reconstruction. As a result of this experience, she and her husband Dr. Ziv Peled (a peripheral nerve and plastic surgeon) began to discuss ways in which they could use their combined, highly specialized skill sets to preserve and restore sensation during mastectomies and implant breast reconstruction. They are now performing sensation preserving mastectomy procedures as well as nipple-sparing mastectomies to patients. They have developed a technique for preserving and grafting nerves that are typically injured during mastectomy. This approach is often performed in combination with nipple-sparing mastectomy and implant breast reconstruction.


Sensation-preserving mastectomies can be offered to those who are diagnosed with breast cancer or those who are at high risk for future breast cancer and are considering prophylactic mastectomy. Sensation preservation at the time of mastectomy involves saving nerves when oncologically safe (meaning the nerves run in the fatty tissue layer beneath the skin) and/or reconstructing nerves that need to be cut during the mastectomy (meaning they run through the breast tissue and do not stay in the fatty tissue layer).

Each person’s situation is unique, so an evaluation to determine if they are a candidate for sensation-preserving mastectomies, as well as if a nipple-sparing mastectomy is right for them and the best choice for their reconstruction, is key to coming up with a final surgical plan. Dr. Anne Peled and her team see patients in-person and through virtual consultation (link to inquiry form) to discuss options and take patients through their surgical journeys.


While mastectomies can be extremely effective at reducing the risk of breast cancer, most women don’t realize that they will have little, if any, sensation in their breast skin or nipple skin afterwards. Because of the way the nerves to the breast skin and nipple travel through the breast tissue, traditional mastectomies tend to cut through these nerves, which leads to breast and nipple numbness for many women, or even sometimes painful sensations at the cut nerve ends. Studies that have looked at sensation after traditional mastectomy consistently show that the majority of women do not ever regain even sensation to light touch throughout their breasts (let alone any pleasurable sensation). Because of the variable nerve anatomy in the breasts, there are some women who may get lucky and have sensation return over time without active preservation of nerves during surgery, but most women will not. With sensation-preserving mastectomy, women are given the opportunity to feel like themselves again after mastectomy without a constant reminder of their surgery as a result of chest numbness.


Dr. Anne Peled has the unique dual training of breast cancer and plastic/reconstructive surgery, which enables her to perform both the mastectomy and reconstruction surgery, a rare combination of skillsets. This, in conjunction with Dr. Ziv Peled’s expertise in peripheral nerve surgery, allowed them to develop a collaborative approach where Dr. Ziv Peled works to keep as many of the nerves to the breast skin as possible while Dr. Anne Peled is performing the mastectomy. Then, for nerves that are unable to be safely preserved, Dr. Ziv Peled uses nerve grafts to reconstruct the cut nerves and provide sensation to the nipple, while Dr. Anne Peled performs the breast reconstruction.


Drs. Anne and Ziv Peled were the first to publish data about this type of surgery. They have found that over 80% of women have sensation that is similar to what they had before surgery, with many women reporting that they often forget they even had mastectomies and reconstruction surgery because their reconstructed breasts feel so much like their breasts prior to surgery.

A sensation-preserving double mastectomy and implant reconstruction takes about three to four hours of surgery, with a one-night hospital or surgery center stay. For recovery after surgery, most women can return to their daily lives and activities within two weeks, with complete recovery in most cases in four to six weeks.



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